ECE Course Outline

ECE4781

Biomedical Instrumentation (3-0-3)

Prerequisites
ECE 3030 [min C] or ECE 3040 [min C] or ECE 3710
Corequisites
None
Catalog Description
A study of medical instrumentation from a systems viewpoint. Pertinent physiological and electro-physiological concepts will be covered. Crosslisted with CHE and ME 4781.
Textbook(s)
Webster, Medical Instrumentation: Application and Design (4th edition), John Wiley, 2009. ISBN 0471676004, ISBN 9780471676003 (required)

Topical Outline
(5 hours) Basic Concepts of Instrumentation 
            Static and dynamic characteristics 
            Design criteria
            Instrumentation Amplifiers

(5 hours) Membrane Biophysics     
            Diffusion across cell membranes
            Nernst potentials
            Diffusion potentials
            Goldman equation

(6 hours) Action Potentials 
            Membrane behavior
            Origin of action potential
            Hodgkin-Huxley equations
            Modeling
            Propagation of action potentials
            Subthreshold stimuli

(4 hours)  Biopotential Electrodes 
             Fundamentals
             Body surface electrodes
             Microelectrodes 

(5 hours) Electrophysiology of the Heart 
            Anatomy/physiology of heart
            Body surface potentials
            Electrocardiogram
            Heart vector
            Standard leads
   
(6 hours) Electrophysiology of Neuromuscular System
            Neuromuscular Junction
            Transmitters
            Poisson statistics for transmitters
            Postjunctional response
            Anatomy/physiology of muscle
            Myofibrils and filaments
            Excitation contraction
            Electromyography   
            Functional neuromuscular stimulation

(3 hours)  Miscellaneous Electrophysiology
             Electroencephalography
             Electroretinogram

(5 hours) Biomedical Transducers
            Displacement transducers
            Thermocouples and thermistors

(4 hours)  Measurement of Blood and Gas Flows
             Electromagnetic flowmeter
             Ultrasonic flowmeter
             Thermodilution catheter

(2 hours)   Exams