Date: Friday, April 29, 2022
Time: 11:00 a.m.
Virtual: See instructions below
Speaker: Janine Bijsterbosch
Speaker’s Title: Assistant Professor, Department of Radiology
Speaker’s Affiliation: Washington University in St. Louis
Seminar Title: Exploring the brain basis of population mental health in the UK Biobank
Join us, Friday, April 29, 2022, at 11 AM ET for an exciting virtual talk by Dr. Janine Bijsterbosch entitled: “Exploring the brain basis of population mental health in the UK Biobank” as part of the activities of the Brain Space Initiative, co-sponsored by the Center for Translational Research in Neuroimaging and Data Science (TReNDS) and the Data Science Initiative, IEEE Signal Processing Society.
Exploring the brain basis of population mental health in the UK Biobank
The UK Biobank is a longitudinal population neuroimaging dataset with extensive neuroimaging, genomic, and phenotypic measures for up to N=100,000 older-age participants. The statistical power, deep phenotyping, and lack of exclusion criteria in this cohort provide an important opportunity to investigate ‘real-world’ mental health. I will present several studies performed in our lab over the past three years to validate UK Biobank mental health measures, identify reproducible multivariate neural correlates of mental health, parse clinical and biological heterogeneity in mental health, and identify lifestyle factors that promote resilience to mental health.
Biosketch: Dr. Bijsterbosch is an Assistant Professor in the Computational Imaging Research Center of the Department of Radiology at Washington University in St Louis. The Personomics Lab headed by Dr. Bijsterbosch aims to understand how brain connectivity patterns differ from one person to the next, by studying the “personalized connectome”. Using population datasets such as the UK Biobank, the Personomics Lab adopts cutting edge analysis techniques to study multivariate imaging measures associated with mental health symptomatology, heterogeneity, and resilience. In addition, Dr. Bijsterboschis an advocate for Open Science serving as Editor of Open Data Replication Reports for the NeuroImagefamily of journals, and as Chair of the Open Science Special Interest Group within the Organization for Human Brain Mapping. Dr. Bijsterbosch is also engaged with international teaching efforts as Co-Chair of the FSL Course Organizing Committee and lead author of a textbook on functional connectivity analyses, which was published by Oxford University Press in 2017.
Recommended Article:
• Dutt, R. K., Hannon, K., Easley, T. O., Griffis, J. C., Zhang, W., & Bijsterbosch, J. D. (2021). “Mental health in the UK Biobank: A roadmap to self‐report measures and neuroimaging correlates.” Human Brain Mapping. Link to Paper
• Zhang, W., Paul, S. E., Winkler, A., Bogdan, R., & Bijsterbosch, J. D. (2022). “Shared brain and genetic architectures between mental health and physical activity.” In bioRxiv. Link to Paper
• Easley, T. O., Chen, R., Hannon, K., Dutt, R. K., & Bijsterbosch, J. D. (2022). “Population modeling with machine learning can enhance measures of mental health - Open-Data Replication.” In bioRxiv(p. 2022.04.04.487069). Link to Paper
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