ECE Course Outline


Quantitative Electrophysiology (3-0-3)

Catalog Description
A quantitative presentation of electrophysiological systems in biological organisms, emphasizing the electrical properties and modeling of neural and cardiac cells and systems. Cross-listed with BMED and PHYS 6787.
Johnson & Wu, Foundations of Cellular Neurophysiology, MIT Press, 1994. ISBN 9780262100533(optional)

Plonsey & Malmivuo, Biolelectromagnetism, Oxford University Press, 1995. ISBN 9780195058239 (required)

Topical Outline
Neurons and Synapses
* More complex ion channel models
* Neuromuscular Junction

Modeling of Electrophysiological Systems
* Measurements/Characterization of Neuronal and Cardiac Behavior
* Pattern Generation in Excitable Media
* Behavioral vs. Functional Modeling
* Parallelism and Connectivity
* Single-cell modeling approaches
* Cable models, length constants

Cardiac Electrophysiology
* Cardiac Muscle Cells and Rhythm Generation
* Bioelectrodynamics of Cardiac Muscle
* Models of Cardiac Cells and Systems

Muscle Physiology  architechture and models

Neural Systems - Examples
* Early Visual Processing
* Auditory Processing and Localization
* Learning of Sensorimotor Mappings
* Oculomotor Control
* Motor Pattern Generation
* Muscular Control and Reflexes

Stimulation and Control of Neural and Cardiac Systems
* Microelectrodes
* Cardiac Defibrillation
* Neural Prostheses
* Dynamic Clamp and similar real-time techniques
* Neural interfacing at the cellular level
* Brain-Computer Interfaces  approaches and state of the art